Mikhail Blagosklonny is famously re-known for his leading role at Roswell Park Cancer Institute, New York whereby he works as a professor of oncology. Having done his master degree and Ph.D. in internal medicine and experimental medicine from the First Pavlov State Medical University of St. Peterburg has helped him attain his first appointment as an associate professor at New York Medical College. With time, Mikhail Blagosklonny would push through his career life by first becoming a senior scientist at Ordway Research Institute and later becoming a professor of oncology at Roswell Cancer Institute in 2009. Roswell Park Cancer Institute is an institution that deals with cancer treatment research in New York. Mikhail has been able to have a leading role in the institute as one of its teaching staff.
As a scientist, Mikhail Blagosklonny primary interest is in cancer therapies and aging. Therefore, he has successfully put forward several theories on tumor suppressors, anti-cancer therapeutics as a mechanism of fighting cancer. He has also come up with rapamycin, which is an anti-aging drug. Furthermore, Mikhail commonly remembered due to his authoring role of hyper- function theory of anti-aging and chemo- therapeutic engineering, which is an anti- cancer approach. Out of his works, he has published many articles and books revolving around this. Henceforth, he has served as chief editor in aging and also cell cycle. Lastly, Mikhail is an associate editor of cancer biology and therapy on Wikipedia, apart from playing a leading role in the membership of the editorial board of Cell death and differentiation.
Dr. Blagosklonny’s hypothesis on the role of Target of Rapamycin (TOR) signaling in aging and cancer broke a milestone in his work. The target of Rapamycin (TOR) is based on determining how the cellular system coordinates its growth, development, and aging in response to constant changes in the immediate environment. These changes are triggered by nutrients that end up regulating growth and metabolism. Rapamycin is an anti- fungal soil bacterium agent that inhibits the growth of the cell. Thus it has an impact on cell cancer and aging. The application of Target of Rapamycin (TOR) leads to developmental mutation or growth arrest hence leading to prolonged lifespan.
Learn more about Mikhail Blagosklonny: https://www.researchgate.net/profile/Mikhail_Blagosklonny